Barnes Manufacturing Co. was an American automobile manufacturer based in Sandusky, Ohio, that operated from 1907 to 1910. The company introduced its first two models in 1907: the Barnes and the SERVITOR. While the SERVITOR was short-lived, lasting only one year, the Barnes model continued production until at least 1910, with some indications that it may have been produced until 1912.

The Barnes was characterized as a roadster equipped with a four-cylinder air-cooled engine. H.C. Barnes is believed to have been a key figure in the company, having taken over the ANHUT Motor Car Co. in 1910, which may have influenced the direction of Barnes Manufacturing Co. during its brief existence.